miRNA326-5p Targets DKC1 Gene to Regulate Apoptosis-Related Proteins and Intervene in the Development of Neuroblastoma

Figure 6

miRNA326-5p interferes with proliferation and apoptosis of NB cells by regulating DKC1 expression. After miRNA326-5p and DKC1 were overexpressed in NB cells: (a) CCK-8 detected the proliferation of cells in each group; (b) cell apoptosis in each group was detected by flow cytometry; (c) the expression of apoptosis-related proteins in each group was detected by Western blot. Mimic-nc was a blank control group, mimic-miRNA326-5p was miRNA326-5p overexpression group, mimic-miRNA326-5p&DKC1 was miRNA326-5p and DKC1 simultaneously overexpression group.

(a)

(b)

(c)