<i>PCSK9-</i>D374Y Suppresses Hepatocyte Migration through Downregulating Free Cholesterol Efflux Rate and Activity of Extracellular Signal-Regulated Kinase

<div>Effect of <i>PCSK9</i> overexpression on HepG2 cell migration. (a) Scratch wound healing assay in HepG2 cells. Photos were taken at 0 h, 24 h, 48 h, 72 h, 96 h, and 108 h at the same place of the scratch wound. At least three independent experiments were conducted with triplicate items. (b) Transwell migration assay of HepG2 cells. Images show representative results. Three random images were collected from each membrane of transwell. Data in (c) show the statistical analysis of (b). At least three independent experiments were conducted with triplicate items. 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Analytical Cellular Pathology

fig5

Figure 5

Figure 5: <i>PCSK9-</i>D374Y Suppresses Hepatocyte Migration through Downregulating Free Cholesterol Efflux Rate and Activity of Extracellular Signal-Regulated Kinase 

Figure 5 | PCSK9-D374Y Suppresses Hepatocyte Migration through Downregulating Free Cholesterol Efflux Rate and Activity of Extracellular Signal-Regulated Kinase 