Research Article
The Accurate Interpretation and Clinical Significance of Morphological Features of Fine Needle Aspiration Cells in Papillary Thyroid Carcinoma
Table 5
The results of smear background, preparation method, and gene detection of patients with papillary thyroid carcinoma and benign lesions (%).
| | Groups | n | PBs | MGCs | Smears | LBP | BRAF |
| | PTC | 337 | 81 (24.04) | 107 (31.75) | 125 (37.09) | 256 (75.96) | 264 (78.34) | | BL | 197 | 0 (0.00) | 90 (45.69) | 18 (9.14) | 179 (90.86) | 0 (0.00) | | TAD | 71 | 0 (0.00) | 41 (57.75) | 4 (5.63) | 67 (94.37) | 0 (0.00) | | NG | 64 | 0 (0.00) | 24 (37.5) | 2 (3.13) | 62 (96.88) | 0 (0.00) | | HD | 23 | 0 (0.00) | 11 (47.83) | 6 (26.09) | 17 (73.91) | 0 (0.00) | | NG and TAD | 39 | 0 (0.00) | 14 (35.90) | 6 (15.38) | 33 (84.62) | 0 (0.00) | | Sensitivity % | (±95% CI) | 24.04 (±4.56) | 31.75 (±4.97) | 37.09 (±5.16) | 75.96 (±4.56)* | 78.34 (±4.40) | | Specificity % | (±95% CI) | 100.00 (±0) | 54.31 (±6.96) | 90.86 (±4.02) | 9.14 (±4.02) | 100.00 (±0) | | Accuracy % | (±95% CI) | 52.06 (±4.23) | 40.07 (±4.16) | 56.93 (±4.20) | 51.31 (±4.24) | 86.33 (±2.91) |
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PTC: papillary thyroid carcinoma; BL: benign lesions; TAD: thyroid adenoma; NG: nodular goiter; HD: Hashimoto’s disease; PBs: psammoma bodies; MGCs: multinucleated giant cells; LBP: liquid-based preparation; GD: gene detection; * as compared to smears. |
