METTL16 Inhibits the Malignant Progression of Epithelial Ovarian Cancer through the lncRNA MALAT1/β-Catenin Axis

Figure 5

METTL16 suppresses EOC progression through the lncRNA MALAT1/β-catenin axis. (a) KEGG enrichment analysis of genes associated with METTL16 and lncRNA MALAT1. (b) Western blotting assay was conducted to determine the protein expression level of β-catenin in SKOV3 cells following the knockdown of METTL16. (c) Western blotting assay was performed to assess the β-catenin expression level in SKOV3 cells subsequent to the combined knockdown of both METTL16 and lncRNA MALAT1. (d) cytoimmunofluorescence staining assay was employed to assess the protein expression level of β-catenin following the knockdown of METTL16 alone or combined knockdown of both METTL16 and lncRNA MALAT1 (scale bar, 50 μm).

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