Research Article
FAP Serves as a Prognostic Biomarker in Head and Neck Squamous Cell Carcinoma
Figure 2
Expression of FAP in HNSCC and its correlation with clinical characteristics. (a) Comparative analysis of FAP expression between neoplastic and normal tissues within the TCGA HNSCC dataset. (b) Differential expression of FAP across disparate tumor stages in HNSCC patients. (c) Comparative FAP expression between TP53-mutated and nonmutated HNSCC patients. (d) Discrepancy in FAP expression contingent upon HPV status (HPV-positive versus HPV-negative) in HNSCC patients. (e) Quantitative PCR (qPCR) elucidation of differential FAP expression between tumoral and peritumoral tissues. (f) Validation of divergent FAP protein expression between neoplastic and adjacent non-neoplastic tissues in a cohort of three HNSCC patients, as ascertained by western blot analysis. .
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