Research Article
The Clinical and Pathological Effects of Serum C3 Level and Mesangial C3 Intensity in Patients with IgA Nephropathy
Table 2
Clinical indicators of patients with decreased C3 and normal C3 group.
| | Laboratory examination | Serum C3 decreased group (<90 mg/dL) | Normal C3 group (≥90 mg/dL) | P Value |
| | FPG (mmol/L) | 5.01 ± 0.4 | 5.2 ± 0.97 | 0.002 | | BUN (mmol/L) | 6.6 ± 3.39 | 6.02 ± 2.4 | 0.006 | | UA (umol/L) | 378.73 ± 112.51 | 389.09 ± 123.4 | 0.816 | | Scr (umol/L) | 98.78 ± 52.3 | 89.67 ± 35.44 | 0.035 | | eGFR (mL/min/1.73 m2) | 93.06 ± 51.6 | 95.62 ± 41.43 | 0.258 | | Alb (g/L) | 38.2 ± 6.3 | 36.33 ± 9.17 | 0.009 | | TC (mmol/L) | 5.72 ± 1.76 | 6.29 ± 2.5 | 0.085 | | LDL-C (mmol/L) | 3.63 ± 1.39 | 3.99 ± 2.09 | 0.046 | | HDL (mmol/L) | 1.32 ± 0.42 | 1.24 ± 0.42 | 0.920 | | TG (mmol/L) | 1.58 ± 0.7 | 2.4 ± 1.66 | 0.011 | | Serum IgA (mg/L) | 329.36 ± 93.84 | 342.19 ± 153.67 | 0.108 | | Serum IgG (mg/L) | 911.15 ± 392.61 | 1012.2 ± 386.87 | 0.492 | | Serum IgM (mg/L) | 118.45 ± 55.91 | 110.05 ± 50.83 | 0.663 | | 24hUP (g/24 hr) | 2.34 ± 1.41 | 3.89 ± 3.17 | 0.001 | | IgA/C3 ratio | 4.65 ± 2.21 | 3.03 ± 1.6 | 0.702 |
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Abbreviations. FPG, fasting plasma glucose; BUN, blood urea nitrogen; UA, uric acid level; Scr, serum creatinine; Alb, albumin; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterin; HDL, high-density lipoprotein cholesterin; TG, triglyceride; 24hUP, 24-hr urinary total protein, 24hUP.
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