Juvenile Myasthenia Gravis: A Paediatric Perspective

Table 1

Comparisons of prepubertal and postpubertal features of JMG.

	Prepubertal	Pubertal	Postpubertal/; adult
Male : female ratio	M = F	F > M 4.5 : 1	F > M 4.5 : 1
Patients with AChR antibodies detected in generalised disease	50–71%; [1, 2]	68–92%; [1, 2]	80–90%
Ocular presentation
Caucasian	40% [7]	9–16% [12]	28% [6]
Chinese	75% [6]
Progression of OMG to generalised MG	8–15%; [17, 18]	23–43%; [16, 19]	79% [8]
Remission (spontaneous or with treatment)	42–60%; [1, 2, 20]	26% [2]	38% [9]