A Tandem Repeat in Decay Accelerating Factor 1 Is Associated with Severity of Murine Mercury-Induced Autoimmunity
Figure 4
Presence of the DBA/2 tandem repeat is associated with reduced immune deposits. Tandem repeat genotypes (D/D, S/S D/S) were compared with features of mHgIA including glomerular deposits of IgG and C3, splenic vessel deposits of IgG and C3, antichromatin autoantibodies (ACA), and antinucleolar autoantibodies (ANoA) in 133 (SJL/JxDBA/2)F2 intercross mice.