Evaluation of a Multiplex ELISA for Autoantibody Profiling in Patients with Autoimmune Connective Tissue Diseases

Table 5

Results for connective tissue diseases group. Concordance between INNO-LIA and Gennova-PictArray.

	INNO-LIA compared with Gennova-PictArray
	Kappa (CI)	Agree (%)
RNP/Sm	0,21 (−0,36–0,77)	92
Ro60	0,22 (0,03–0,42)	58
Ro52	0,63 (0,47–0,79)	81
SSB	0,71 (0,54–0,88)	88
Jo1	not defined	—
Sm Antigen	0,22 (−0,38–0,82)	93
Scl70	0,66 (0–1,32)	99
CENP-B	0,66 (0–1,32)	99

Kappa coefficient (0.01–0.2 indicates poor agreement, 0.21–0.4 is fair, 0.41–0.6 is moderate, and 0.61–0.8 is substantial agreement, 0.81–0.99 is almost perfect agreement).