The Attenuated Live Yellow Fever Virus 17D Infects the Thymus and Induces Thymic Transcriptional Modifications of Immunomodulatory Genes in C57BL/6 and BALB/C Mice

Figure 6

Comparison of transcriptional profiles of (a) H2-T23 (Qa-1/HLA-E) and (b) FOXP3 in thymus of C57BL/6 and BALB/c mice inoculated with 10.000 LD₅₀ of YFV17D. RQ = relative quantification representative of geometric mean values of . RQ values expressed as fold change relative to control group values (baseline = 1). Statistical analysis was performed using the nonparametric test Mann-Whitney two-tailed. Values close to the level of significance () are marked with .

(a)

(b)