Research Article

Comparing Long-Term Outcomes of Entecavir and Tenofovir Disoproxil Fumarate in Liver Transplant Patients

Table 2

Baseline characteristics of recipients and donors after matching.

VariableEVT ()TDF ()SD value

Recipient age (years)0.020.822
Recipient gender (, % female)55 (13.4%)10 (9.7%)0.110.320
Recipient BMI (kg/m2)0.020.837
Recipient HCC (, %)197 (47.8%)46 (44.7%)0.060.566
Hypertension (, %)65 (15.8%)19 (18.5%)0.070.512
Diabetes mellitus (, %)66 (16.0%)20 (19.4%)0.090.408
MELD at transplantation15 (10-25)14 (9-26)0.010.932
Baseline eGFR (mL/min/1.73 m2)107 (94-116)108 (94-119)0.080.539
HBsAg (log10 U/mL)2.53 (1.62-3.20)2.41 (1.43-3.32)0.020.942
HBV DNA detectable189 (45.9%)49 (47.6%)0.030.757
Donor age (years)0.020.888
Donor gender (, % female)65 (15.8%)17 (16.5%)0.020.857
Donor BMI (kg/m2)0.010.923
Cold ischemic time (hours)0.020.890
Duration of surgery (hours)0.010.896
Blood loss (100 mL)10 (6-15)10 (6-15)0.040.695
ABO incompatibility (, %)58 (14.1%)16 (15.5%)0.040.706
Recipient severe postoperative complications (, %)136 (33.0%)31 (30.1%)0.060.572

Abbreviations: ENT: entecavir; TDF: tenofovir; HBsAg: hepatitis B surface antigen; MELD: Model for End-stage Liver Disease; BMI: body mass index; HBV: hepatitis B; HCC: hepatocellular carcinoma; SD: Standardized difference; eGFR: estimated glomerular filtration rate.