| | Clinical characteristics | Number of patients (%) | Preoperative fibrinogen levels (g/L) | value |
| | Gender | | | | | Male | 86 (33.08) | 3.46 (2.71,4.47) | 0.225 | | Female | 174 (66.92) | 3.25 (2.67,3.99) | | Age (yrs) | | | | | ≤60 | 78 (30.00) | 3.19 (2.53,3.74) | 0.017 | | >60 | 182 (70.00) | 3.41 (2.72,4.42) | | Smoking history | | | | | Yes | 55 (21.15) | 3.39 (2.72,4.30) | 0.714 | | No | 205 (78.85) | 3.32 (2.67,4.20) | | Drinking history | | | | | Yes | 47 (18.08) | 3.46 (2.84,4.59) | 0.115 | | No | 213 (81.92) | 3.25 (2.67,4.01) | | BMI (kg/m2) | | | | | >22.62 | 104 (50.98) | 3.25 (2.66,4.06) | 0.503 | | ≤22.62 | 100 (49.02) | 3.32 (2.72,4.20) | | Tumor location | | | | | Neck | 50 (24.75) | 3.46 (2.80,4.44) | 0.162 | | Body+fundus | 152 (75.25) | 3.17 (2.56,4.00) | | Tumor size (cm) | | | | | >3.5 | 114 (45.60) | 3.16 (2.55,3.84) | 0.001 | | ≤3.5 | 136 (54.40) | 3.50 (2.97,4.51) | | Differentiation | | | | | Poorly | 133 (51.15) | 3.46 (1.80,6.50) | 0.013 | | Well | 127 (48.85) | 3.22 (2.56,3.87) | | Pathological type | | | | | Adenocarcinoma | 239 (91.92) | 3.28 (2.65,4.16) | 0.114 | | Others | 21 (8.08) | 3.52 (2.24,12.80) | | Vascular invasion | | | | | Positive | 54 (20.77) | 3.43 (2.78,4.34) | 0.604 | | Negative | 206 (79.23) | 3.32 (2.64,4.17) | | Nerve invasion | | | | | Positive | 64 (24.62) | 3.46 (3.03,4.45) | 0.157 | | Negative | 196 (75.38) | 3.26 (2.64,4.14) | | Cancerous node | | | | | Positive | 13 (5.00) | 3.32 (2.87,3.80) | 0.888 | | Negative | 247 (95.00) | 3.33 (2.65,4.33) | | TNM stage | | | | | I+II | 98(37.69) | 2.84 (2.40,3.55) | <0.001 | | III+IV | 162 (62.31) | 3.51 (3.00,4.48) | | CEA (ng/mL) | | | | | >2.17 | 164 (63.08) | 3.37 (2.69,4.30) | 0.4543 | | ≤2.17 | 96 (36.92) | 3.25 (2.58,4.20) | | CA19-9 (U/mL) | | | | | >41.1 | 114 (43.85) | 3.55 (3.07,4.48) | <0.001 | | ≤41.1 | 146 (56.15) | 3.16 (2.51,3.99) |
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