Alkylresorcinols as a New Type of Gut Microbiota Regulators Influencing Immune Therapy Efficiency in Lung Cancer Treatment

Figure 3

The representation of AR content in serum of healthy people and lung cancer patients. (a) A volcano plot based on multiple Mann–Whitney tests of AR content in serum of healthy people and lung cancer patients; the volcano graph represents the changes in AR levels between different cohorts of serum donors (the value reflects a false discovery rate of 20%); the mean rank difference values reflect the direction of changes in the AR level (values below zero indicate an increase in the AR level in serum, while values above zero indicate a decrease in the AR level in serum of human donors); statistically significant values are marked with red dots. (b) Differences in C12 (dodecylresorcinol) content in serum samples from healthy people and lung cancer patients according to unpaired Mann–Whitney test (). Black bar indicates AR value (nmol/l) in serum of healthy donors; orange bar indicates AR value (nmol/l) in serum of lung cancer patients.

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