Enrichment of Lactic Acid-Producing Bacteria in the Fecal Microbiota of Patients with Ulcerative Colitis in North India

Figure 7

Differential metabolic pathways observed between UC subgroups and healthy controls. (a) PCA plot based upon metabolic pathways enrichment. (b) Total number up (increase) and down (decrease) regulated metabolic pathways. (c) Venn diagram representing overlap and different metabolic pathways. (d–f) Log fold change in the unique metabolic pathway observed between comparative groups. (g) Relative abundance of selected shared metabolic pathways (lactose degradation) between active and healthy and remission and healthy. (h, i) Relative abundance of selected downregulated metabolic pathways (pyruvate fermentation to butanoate and SCFA producer) between active and healthy. value is Mann–Whitney with Bonferroni correction.

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