Investigating the Impact of HTNV Infection on the Gut Microbiota of Wild-Type and NLRX1 Knockout Mice

Figure 2

Alterations to α and β diversity of gut microbiota have been observed in both WT and Nlrx1^-/- mice due to HTNV infection. (a) Among the 381 OUTs identified, 247 were determined to be core OTUs in the two groups. (b) The Shannon diversity index was used to estimate α diversity; WT: at each time point; Nlrx1^-/-: at each time point. (c) The Tukey HSD test was utilized to draw a box line diagram of the α diversity index, with a significance level of . (d) Through principal coordinate analysis (PcoA) based on unweighted UniFrac distances, β diversity was analyzed. PCo1 and PCo2 were the principal coordinates that accounted for the majority of the diversity.

(a)

(b)

(c)

(d)