Assessment of Ameliorative Effect of Myrica esculenta in a DSS-Induced Murine Model against Ulcerative Colitis

Figure 2

Effect of MeEt extract on body weight and disease activity index (DAI) against DSS-induced UC in mice. UC was induced in all the groups except vehicle control group by treating animals with the DSS (3%) in drinking water for 7 days. Mesalazine/MSZ (100 mg/kg BW) was administered orally as a standard drug. MeEt extract was administered orally at the doses of 200 and 400 mg/kg BW once a day for 7 days: (a) % of initial body weight; (b) average food intake per mouse (g); (c) mean stool consistency score; (d) mean stool blood score. All data are presented as (). Tukey’s multiple comparison test along with a one-way ANOVA was utilized to identify the significant differences among the groups. ^###, ^##, and ^#, DSS control group vs. vehicle control group; , , and , treatment groups vs. DSS control group.

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