Review Article
Gut Microbiome: An Intersection between Human Genome, Diet, and Epigenetics
Table 1
Gene variants and their associated microbiota.
| Gene | Microbiota | Related condition | References |
| NOD2 | Increase Escherichia spp. and decrease Faecalibacterium spp. | IBD | [35] | NOD2/ATG16L1 | Increase Bacteroides fragilis | IBD | [51] | UBR3 | Increase Rikinellaceae spp. | Dysregulation of the protein ubiquitination pathway | [72] | PLD1 & LINGO2 | Increase Akkermansia and Blautia spp. | Obesity | [72] | SLIT3 | Increase Clostridiaceae and Dermococcus spp. | Inflammation and obesity | [2] | VDR3 | Increase Parabacterioides spp. | Dysregulation of bile synthesis | [94] | ALDH1AL1 | Increase Christensenelleceae spp. | Dysregulation of xenobiotic metabolism | [2] | PTN2 & PTN22 | Increase Faecalibacterium, Bilophilia, and Coprococcus spp. | T1D | [83, 85] | DR3/4 | Increase Bacteroides, Parabacteroides, Clostridium, Klebsiella, and Akkermansia spp. | T1D | [89] |
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