DNMT3A Mutations in Patients with Acute Myeloid Leukemia in South Brazil

Table 5

Clinical characteristics of patients with acute myeloid leukemia with or without DNMT3A mutations.

Characteristics	Number of pts (%); DNMT3A mutated	Number of pts (%); DNMT3A not mutated	𝑃
Age (median)	40.2	44.8	0.56
Sex
Male	50%  (3)	59.3%  (45)	0.68
Female	50%  (3)	40.7%  (31)
Subtype FAB
M0	0%	7.2%  (5)
M1	60%  (3)	18.8%  (13)
M2	20%  (1)	30.4%  (21)	0.56
M3	20%  (1)	20.3%  (14)
M4	0%	18.8%  (13)
M5	0%	1.4%  (1)
Not M3	0%	2.9%  (2)
Risk groups
Favorable	20%  (1)	29.8%  (17)
Intermediate	80%  (4)	59.6%  (34)	1.000
Unfavorable	0%	10.5%  (6)
Leukocytes (×10^3) (median)	20.67	6.41	0.28
Death	50%  (3)	51.4%  (37)	1.000
Relapses	50%  (2)	30.9%  (17)	0.58
Refractory	20%  (1)	19.1%  (13)	0.96