Clinical Study

Imatinib Mesylate Effectiveness in Chronic Myeloid Leukemia with Additional Cytogenetic Abnormalities at Diagnosis among Black Africans

Table 1

Epidemiological, clinical, and biological features of patients.

VariablesNumbers (%)

Age (years) mean age 38 years (13–68)
 11–3013 (48)
 31–509 (33)
 51–705 (19)
Sex
 Male18 (67)
 Female9 (33)
Socioeconomic level
 Low10 (37)
 Average17 (63)
Reason for consultation
 Hyperleukocytosis17 (63)
 Hyperleukocytosis + splenomegaly10 (37)
Performance status
 0 and 10 (0)
 2 and 313 (48)
 414 (52)
Bone pains
 Presence13 (48)
Fever
 Presence20 (74)
Hepatomegaly
 Presence13 (48)
Lymphadenopathy
 Presence6 (22)
Splenomegaly
 0 cm0 (0)
 1–9 cm7 (26)
 ≥10 cm7 (26)
Hemogram (median values and extremes)
 White Blood Cells (109/L)341.2 (140–650)
 Hemoglobin (g/dL)8.5 (5.7–12.4)
 Platelets (109/L)340 (57–1992)
 Polynuclear basophiles (%)5 (0–9)
 Blasts (%)7 (0–16)
 Promyelocytes (%)8 (0–18)
Sokal score
 Low0 (0)
 Intermediate9 (33)
 High18 (67)