Research Article
Vitamin D and Nonskeletal Complications among Egyptian Sickle Cell Disease Patients
Table 2
Demographic and laboratory data of the case and control groups.
| | Variable | Case(n=80) | Control(n=60) | P-value |
| | Age: in years:median (IQR) | 9 (7.5) | 9.5 (8) | 0.753 |
| | Sex: n (%) | | | 0.522 | | Male (%) | 47 (58.8%) | 34 (56.6%) | | | Female (%) | 33 (41.2%) | 26 (43.3%) | |
| | Hemoglobin (g/dl): mean ± SD | 8.3 ±1.4 | 13.2 ±1.8 | Less than 0.001 |
| | Hematocrit (%): mean ± SD | 25.5 ±4.8 | 37 ±3.9 | Less than 0.001 |
| | MCV (FL): mean ± SD: | 84.5 ±8.8 | 88.1 ± 6.8 | 0.008 |
| | MCH (pg): mean ± SD | 25.0 ±3 | 32.3 ±1.7 | Less than 0.001 |
| | WBC (103mm2): mean ± SD | 9.2 ±4.4 | 7.9 ±2.1 | 0.033 |
| | Platelets (10 3mm2): mean ± SD | 328.2 ±164.4 | 284.7 ±106.4 | 0.067 |
| | 25-OHD (ng/ml): mean ± SD | 22 ±10.4 | 22.7±8.4 | 0.658 |
| | No Deficiency: n (%) | 32 (40%) | 44(73.3%) | 0.061 |
| | Deficiency: n (%) | 48 (60%) | 16 (26.7%) | 0.058 |
| | Severe deficiency: n (%) | 13 (16.2%) | 5 (8.3%) | 0.021 |
| | 25-OHD in VDD groups (ng/ml): mean ± SD | 9.9 ±2.1 | 11±1.8 | 0.049 |
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n= number. IQR= interquartile range. SD = standard deviation. 25-OHD =25-hydroxyvitamin D. MCV = mean corpuscular volume. MCH= mean corpuscular hemoglobin. WBC= white blood cells. VDD= vitamin D deficiency. Bold values indicate statistical significance.
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