Effect of Imatinib on Bone Marrow Morphology and Angiogenesis in Chronic Myeloid Leukemia

Figure 1

(a) Pre therapy histological section of bone marrow biopsy stained by Gomori reticulin stain (400x magnification) showing diffuse and dense increase in reticulin with extensive intersections with coarse bundles of collagen (grade 3 fibrosis). (b) Post therapy histological section of bone marrow biopsy of the same patient (400x magnification) showing scattered linear reticulin with no intersections (grade 0 fibrosis).

(a)

(b)