IL-31 and IL-8 in Cutaneous T-Cell Lymphoma: Looking for Their Role in Itch

Figure 1

IL-31 (a) and IL-8 (b) serum levels according to diagnosis and to the presence of itch. In this figure, 2 outliers were excluded for sIL-31 (sIL-31 > 200 pg/mL) and 1 outlier was excluded for IL-8 (sIL-8 > 200 pg/mL). Statistical analysis was performed using the Mann–Whitney U test. ; ; and . Statistics for sIL-31 (including/excluding the outliers): CTCL vs. controls: /; MF vs. controls: /; SS vs. controls: /; MF vs. SS: /; CTCL without itch vs. controls: /; CTCL with itch vs. controls: /; and CTCL with itch vs. CTCL without itch: /. Statistics for sIL-8 (including/excluding 1 CTCL outlier, corresponding to a patient with hyperleukocytosis and sIL-8 >200 pg/mL): CTCL vs. controls: /; MF vs. controls: /; SS vs. controls: /; MF vs. SS: /; CTCL without itch vs. controls: /; CTCL with itch vs. controls: /; and CTCL with itch vs. CTCL without itch: /. CTCL, cutaneous T-cell lymphoma; MF, Mycosis Fungoides; SS, Sézary syndrome; sIL-8, interleukin-8 serum levels; and sIL-31, interleukin-31 serum levels.

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