Research Article

To Measure or Not to Measure: Direct Oral Anticoagulant Laboratory Assay Monitoring in Clinical Practice

Table 1

Patient baseline characteristics.

Overall N = 119Apixaban n = 62Rivaroxaban n = 57

Age, years: median (IQR)74 (27–102)78 (33–102)69 (27–91)
 <65 years37 (31)13 (21)24 (42)
 65–74 years26 (22)11 (18)15 (26)
 ≥75 years56 (47)38 (61)18 (32)
Sex
 Male60 (50)31 (50)29 (51)
 Female 59 (50)31 (50)28 (49)
Body Mass index, kg/m2: median (IQR)26.8 (17–64)26.0 (17–49)26.9 (17–64)
 ≥3516 (13)6 (10)10 (18)
 30–34.918 (15)11 (18)7 (12)
 25–29.943 (36)22 (35)21 (37)
 18.5–24.933 (28)17 (27)16 (28)
 <18.54 (3)3 (5)1 (2)
 Unknown5 (4)3 (5)2 (3)
Past medical history
 Gastrointestinal bleed8 (7)7 (11)1 (2)
 Stroke/TIA28 (24)18 (29)10 (18)
 eGFR <60 mL/min33 (28)26 (42)7 (12)
 Diabetes27 (23)18 (29)9 (16)
Indication for anticoagulant
 Stroke prevention with atrial fibrillation49 (41)14 (12)35 (29)
 Acute PE28 (24)16 (28)12 (19)
 Chronic PE14 (12)12 (21)2 (3)
 Acute DVT31 (26)18 (32)13 (21)
 Chronic DVT24 (20)19 (33)5 (8)
 Other9 (8)4 (7)5 (8)