Angiogenesis and erythropoiesis gene expression (transcription), Assembly of the prereplicative complex
Hypermethylation of RARbCpG islands was identified in 29.7% of the analyzed samples in a group of patients while in another series, it was found in 3.1% of the samples studied
Gene expression (transcription) innate immune system oxidative stress
A distal CpG island in the promoter region remained methylated both in normal B cells and CLL cells, while variable methylation levels were recorded in the proximal CpG island only in CLL cells exposure of CLL cells to a demethylating agent led to increased catalase mRNA levels