Research Article

Challenges and Outcomes of the First Stem Cell Transplant Program in Tanzania, East Africa

Table 2

Assessment tool.

Infrastructure of the stem cell transplant unit
(i) HEPA-filtered rooms with attached washroom
(ii) Clean and dirty utility areas
(iii) Biomedical equipment: infusion and syringe pumps, cardiac monitors, medication carts, crash cart, computers for accessing the hospital and laboratory information systems

Apheresis facility
(i)Apheresis equipment × 2
(ii) Appropriate stem cell harvest kit
(iii) ACD bags and other consumables

Stem cell laboratory for CD34+ cell enumeration and stem cell storage
(i) Flow cytometer with updated software
(ii) Reagents for standardization of CD34+ cell enumeration
(iii) CD34+ cell enumeration beads and reagents
(iv) Controlled rate freezer with liquid nitrogen storage tank
(v) Liquid nitrogen shipper
(vi) Liquid nitrogen supply
(vii) Trained laboratory technologist

Team
(i) Attending physicians
(ii) Associate physicians
(iii) Registered nurses
(iv) Clinical pharmacist
(v) Housekeeping staff

Policies and protocols
(i) Standard operating protocols (SOP) for pretransplant workup and consent
(ii) Nursing policies and SOPs
(iii) Infection control policy
(iv) Febrile neutropenia management policy
(v) Central venous access insertion and maintenance bundle
(vi) Transfusion policy
(vii)SOPs for peripheral blood stem cell harvest, storage, transport and infusion

Drugs
(i) Antibiotics and antifungals
(ii) G-CSF
(iii) Plerixafor
(iv) Chemotherapeutic drugs

Allied departments
(i) Intensive care unit
(ii) Transfusion medicine service with availability of blood components
(iii) Laboratory with a quality management plan for hematologic and biochemistry tests and for blood culture and sensitivity
(iv) Dietetics department with hygiene control and pest control
(v) Radiology department with the ability to insert central venous catheters