Challenges and Outcomes of the First Stem Cell Transplant Program in Tanzania, East Africa

Table 5

Key challenges for the stem cell harvest and engraftment.

Challenges	Intervention	Result	Future
Assumed difficulty in the pre- harvest enumeration	Inj. PLERIXAFOR 24 mg S/C for all patients during 1^st camp	Adequate stem cell collection (except one patient who required 2 days collection)	Camp 2- Reliable CD34 cell enumeration – Inj. PLERIXAFOR required only for 1 patient
Limitation in the number of apheresis kits and consumables
Venous access	CVC (femoral)- camp 1–5 patients	Apheresis procedure uneventful	Camp 2- CVC required only for 1 patient
Febrile neutropenia management	Inj. Peg G-CSF 6 mg SC weekly from day +3 until engraftment	Early engraftment