Research Article
CYP4F2 (rs2108622) Gene Polymorphism Association with Age-Related Macular Degeneration
Table 4
Frequency of CYP4F2 rs2108622 genotype in early AMD patients, in eAMD patients and controls by age.
| | Genotype | <65 years | value | ≥65 years | value | AMD group
(%) | Control group
(%) | AMD group
(%) | Control group
(%) |
| | Frequency of CYP4F2 (1347C>T; V433M) rs2108622 genotype in the patients with early AMD and the control subjects by age | | TT | 4 (4.5) | 11 (7.1) | 0.538 | 7 (6.9) | 5 (9.3) | 0.847 | | TC | 39 (43.8) | 59 (37.8) | 42 (41.6) | 23 (42.6) | | CC | 46 (51.7) | 86 (55.1) | 52 (51.5) | 26 (48.1) | | Allele | | | | | | T | 47 (26.4) | 81 (25.96) | 56 (27.72) | 33 (30.55) | | C | 131 (73.6) | 231 (74.04) | 146 (72.28) | 75 (69.45) |
| | Frequency of CYP4F2 (1347C>T; V433M) rs2108622 genotype in the patients with eAMD and the control subjects by age | | TT | 1 (3.8) | 11 (7.1) | 0.751 | 6 (3.9) | 5 (9.3) | 0.266 | | TC | 9 (34.6) | 59 (37.8) | 63 (40.6) | 23 (42.6) | | CC | 16 (61.5) | 86 (55.1) | 86 (55.5) | 26 (48.1) | | Allele | | | | | | T | 11 (21.15) | 81 (25.96) | 75 (24.19) | 33 (30.55) | | C | 41 (78.85) | 231 (74.04) | 235 (75.81) | 75 (69.45) |
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value: significance level (alpha = 0.05); value HWE: significance level (alpha = 0.05) by Hardy-Weinberg equilibrium.
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