Preparation and Characterization of Sodium Alginate/Chitosan Composite Nanoparticles Loaded with Chondroitin Sulfate

Figure 8

Cumulative release profiles of the CS/SA/chitosan composite nanoparticles prepared with a weight ratio of SA to CS of (a) 2 : 1 and (b) 1 : 1; SA to chitosan and SA to calcium chloride of 1 : 1 and 3 : 17, respectively, in simulated gastric (pH = 1.2) and intestinal (pH = 6.8) media at 37°C.