Research Article
In Vitro Evaluation of Native Taro Boloso-I Starch as a Disintegrant in Tablet Formulations
Table 3
Weight, thickness, TBF, friability, and DT values of paracetamol tablets prepared with NTBIS as disintegrant.
| | | Weight (mg) | Thickness (mm) | TBF (N) | Friability (%) | DT (min) |
| | F1 | 351.7 ± 3.5 | 3.96 ± 0.05 | 97.30 ± 6.0 | 0.150 ± 0.10 | 14.10 ± 0.9 | | F2 | 350.3 ± 4.9 | 3.91 ± 0.04 | 131.00 ± 5.9 | 0.200 ± 0.02 | 2.65 ± 0.0 | | F3 | 349.0 ± 3.8 | 3.94 ± 0.07 | 110.75 ± 8.8 | 4.000 ± 0.60 | 43.00 ± 0.6 | | F4 | 349.5 ± 4.1 | 3.90 ± 0.04 | 161.32 ± 5.7 | 0.200 ± 0.02 | 3.00 ± 0.3 | | F5 | 350.2 ± 2.9 | 3.95 ± 0.05 | 107.00 ± 11.2 | 0.600 ± 0.17 | 42.50 ± 0.3 | | F6 | 349.8 ± 6.0 | 3.89 ± 0.04 | 153.43 ± 6.8 | 0.100 ± 0.02 | 2.08 ± 0.1 | | F7 | 350.0 ± 3.0 | 3.94 ± 0.08 | 99.20 ± 3.4 | 0.175 ± 0.08 | 3.02 ± 0.5 | | F8 | 350.1 ± 3.1 | 3.93 ± 0.06 | 143.00 ± 6.1 | 2.880 ± 0.47 | 10.20 ± 0.3 | | F9 | 350.0 ± 2.8 | 3.93 ± 0.05 | 141.50 ± 5.6 | 0.233 ± 0.01 | 6.40 ± 0.4 | | F10 | 351.8 ± 3.0 | 3.94 ± 0.06 | 138.25 ± 6.3 | 0.200 ± 0.04 | 6.30 ± 0.3 | | F11 | 351.0 ± 4.5 | 3.93 ± 0.05 | 141.50 ± 5.1 | 0.195 ± 0.03 | 6.30 ± 0.1 | | F12 | 350.5 ± 4.5 | 3.94 ± 0.06 | 138.00 ± 3.5 | 0.217 ± 0.04 | 2.40 ± 0.3 | | F13 | 350.0 ± 3.0 | 3.93 ± 0.04 | 137.10 ± 5.7 | 0.198 ± 0.03 | 2.60 ± 0.6 |
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