Research Article
In Vitro Evaluation of Native Taro Boloso-I Starch as a Disintegrant in Tablet Formulations
Table 5
The TBF, friability, disintegration time, and DER of tablets prepared with NTBIS and potato starch at optimum levels of factors.
| | | | TBF (N) | Friability (%) | DT (min) | DER (N/(%Min)−1 | DERc |
| | NTBIS | B1 | 112.3 ± 6.5 | 0.190 ± 0.02 | 1.31 ± 0.17 | 476.0 | 9.3 | | B2 | 116.0 ± 6.1 | 0.15 ± 0.02 | 1.35 ± 0.19 | 582.7 | 15.2 | | B3 | 122.2 ± 6.8 | 0.13 ± 0.02 | 1.39 ± 0.11 | 685.9 | 16.3 | | µ ± SD | 116.8 ± 7.5 | 0.157 ± 0.03 | 1.35 ± 0.16 | 581.6 | 13.6 | | PV | 116.2 | 0.153 | 1.36 | 562.3 | | | ɛ | 0.52 | 2.61 | −0.74 | 3.43 | | | Potato starch | B1 | 58.5 ± 6.0 | 0.96 ± 0.02 | 1.20 ± 0.06 | 50.8 | — | | B2 | 50.4 ± 5.8 | 1.08 ± 0.30 | 1.23 ± 0.06 | 40.0 | — | | B3 | 54.7 ± 4.8 | 1.01 ± 0.07 | 1.3 ± 0.04 | 42.1 | — | | µ ± SD | 54.8 ± 6.4 | 1.01 ± 0.18 | 1.24 ± 0.07 | 44.3 | — |
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B, DER, DER c, PV, and ɛ stand for batch number, disintegration efficiency ratio, relative disintegration efficiency ratio, predicted value, and percent error, respectively. |
