Semicontinuous Blending of Pharmaceutical Ingredients and the Impact of Process Parameters on the Blending Performance of an Integrated Feeder Blender Operating Semicontinuously

Table 3

DOE experiment parameters, RSD results, and CI results.

S. no.	Impeller rotation per minute	Blending time (min)	Fill levels (%)	Relative standard deviation	Carr index
1	160	1	30	5.34	19.77
2	160	5	30	2.9	20.33
3	160	5	70	2.99	21.41
4	120	3	50	3.82	19.68
5	80	5	70	18.5	18.89
6	120	3	50	4.12	19.78
7	120	3	50	4.44	19.51
8	80	5	30	16.8	18.83
9	160	1	70	5.88	20.12
10	80	1	70	21.3	18.89
11	80	1	30	19.23	18.62