Research Article

High-DNA Stainability Is Not Related to Embryonic Development and Clinical Outcomes on In Vitro Fertilization Cycles: A Retrospective Study Using a Propensity Score-Matching Analysis

Table 1

Baseline characteristics of IVF cycles of the HDS > 15% group and the HDS ≤ 15% group after matching.

HDS > 15% group (n = 676)HDS ≤ 15% group (n = 1928)P-value

HDS (%)19.01 (16.54, 24.32)8.04 (6.15, 10.40)<0.001
Male age (year)34.00 (31.00, 38.00)34.00 (30.75, 38.00)0.564
Sperm concentration (million/ml)55.95 (35.90, 91.83)59.60 (37.80, 94.48)0.175
Progressive sperm motility (%)43.60 (33.48, 53.82)45.20 (33.30, 56.90)0.140
Morphologically normal spermatozoa (%)5.25 (4.10, 7.20)5.50 (4.20, 7.60)0.264
DFI (%)9.38 (6.15, 14.31)9.02 (5.65, 14.24)0.102
Female age (year)32.00 (29.00, 36.00)32.00 (29.00, 35.00)0.760
Female BMI (kg/m2)21.34 (19.64, 23.24)21.23 (19.63, 23.23)0.527
Endometrial thickness on the day of ovulatory dose of hCG (mm)10.00 (8.00, 12.00)10.00 (8.00, 12.00)0.695
Duration of infertility (year)3.00 (1.50, 4.00)3.00 (1.00, 4.00)0.974
Cause of infertility
Female factor, n (% per included cycle)359 (53.11)1023 (53.06)1.000
Male factor, n (% per included cycle)102 (15.09)268 (13.90)0.443
Female and male factor, n (% per included cycle)61 (9.02)182 (9.44)0.818
Unexplained, n (% per included cycle)154 (22.78)455 (23.60)0.712
Retrieved oocytes (n)12.00 (7.00, 19.00)13.00 (8.00, 19.00)0.454

Note: DFI, DNA fragmentation index; BMI, body mass index.