Ejaculatory Duct Obstruction Affects Seminal Vesicle Contractile Efficacy and Smooth Muscle Ultrastructure in a Rat Model

Figure 5

Representative ultrastructural photographs of seminal vesicle smooth muscle cells from rats in the complete EDO group at 4 (a, b) and 8 (c, d) weeks. (a) Smooth muscle cells pyknosis, lobulated nucleus (N), and a large number of collagen fibers (CFs) in the intercellular space (magnification ×2.0 k). (b) Reduced number of mitochondria (Mit) around the nucleus (magnification ×6.0 k). (c) Pyknosis of smooth muscle cells, accompanied by nuclear karyolysis and marked reduction of dense plaques (Dps) in the cytoplasm. Lipid droplets (LDs) can be seen in the cytoplasm, and a large number of intricately arranged collagen fibers (CFs) can be seen in the interstitium (magnification ×2.0 k). (d) The number of dense bodies (Dbs) was significantly reduced. Mitochondria (Mit) reduced and partially pyknosis; rough endoplasmic reticulum (rER) expanded (magnification ×6.0 k).

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