Research Article

Outcomes of Microdissection Testicular Sperm Extraction/Intracytoplasmic Sperm Injection in Cases of Nonobstructive Azoospermia: A Retrospective Study

Table 2

Outcomes of intracytoplasmic sperm injection (ICSI) in men with NOA with successful sperm retrieval and in men with obstructive azoospermia (OA).

VariableNOAOA value

Number of cycles101329
Female age29 (26–31.5)31 (28–35)<0.01
Infertility duration (years)3 (2–6)3.5 (2–6)0.265
Follicles punctured ()0.075
Total oocytes ()0.096
MII oocytes ()11 (9–15)10 (6–14.5)0.038
Oocytes used for ICSI ()11 (9–15)10 (6–14)0.049
Zygotes ()8 (4–10)7 (4–11)0.385
Fertilization rate (%)65.04% (761/1170)78.57% (2771/3527)<0.01
Two-pronuclear (2PN) zygotes ()7 (4–9)7 (4–10.5)0.368
2PN fertilization rate (%)59.40% (695/1170)70.68% (2493/3527)<0.01
2PN cleavages ()3.5 (7–9)4 (7–10)0.395
2PN cleavage rate (%)98.85% (687/695)97.99% (2443/2493)0.136
High-quality embryos ()2 (1–5)3 (1–6)0.211
High-quality embryo rate (%)49.05% (337/687)51.58% (1260/2443)0.243
Blastocysts formed ()1 (0–3.5)2 (0–4)0.357
Blastocyst formation rate (%)55.21% (212/384)56.72% (814/1435)0.595
Available blastocysts ()0 (0–2)1 (0–2)0.323
Available blastocyst rate (%)72.64% (154/212)70.39% (573/814)0.521

; all other data are presented as median (interquartile range) or percentage (number ratio); .