Research Article

The Effect of Thyme Honey on the Histopathological Changes of the Testis in Relation to the Side Effects of Valproic Acid in Adult Male Wistar Rats

Table 4

Effect of thyme honey and VPA on epididymal spermatozoa.

Parameter (%)Groupp-Value
ControlTh1Th2Th3VPAVPA + Th1VPA + Th2VPA + Th3

Viability70.081 ± 1.57a78.94 ± 6.1a75.59 ± 3.78a80.46 ± 3.97a55.07 ± 1.13b69.98 ± 5.04a73.19 ± 3.10a70.89 ± 1.21a<0.0001
Dead spermatozoa29.92 ± 1.57b21.06 ± 6.1b24.41 ± 3.78b19.54 ± 3.97b44.93 ± 1.13a30.02 ± 5.04b26.81 ± 3.10b29.11 ± 1.21b<0.0001
Motility62.29 ± 4.04ab73.32 ± 4.84a75.37 ± 7.22a72.44 ± 10.75a45.00 ± 10.26b59.32 ± 15.58ab64.68 ± 10.68a69.42 ± 8.94a<0.0001

Note: Thyme honey consumption in contrast to the VPA significantly increased the percentage of sperm parameters (motility and viability) and decreased dead spermatozoa. a,b,abValues with different superscript characters indicate significant difference between the control and treatment groups. Groups with the same superscript letter do not differ significantly.