Evaluation of the Combination of Recombinant FSH and Antioxidant Therapy on DNA Fragmentation Index (DFI) in Infertile Men

Table 2

Descriptive statistics of semen and sperm DFI analysis before and after the treatment.

Variables	Total participants ()
	Before	After	value
Sperm DNA fragmentation index (DFI) (%) (median (IQR))	32.5 (17.0)	15.0 (10.2)	≤0.001^b
Sperm chromatin immaturity (%) (median (IQR))	11.0 (7.0)	9.0 (9.0)	0.138^b
Sperm concentration (10^6/ml) (mean (SD))	26.9 (15.0)	25.9 (13.9)	0.300^a
Total sperm count (10^6) (median (IQR))	70.0 (68.0)	44.9 (41.3)	0.006^b
Total motility (%) (median (IQR))	50.0 (20.0)	50.0 (15.0)	0.120^b
Progressive motility (%) (median (IQR))	25.0 (15.0)	22.5 (15.0)	0.658^b
Nonprogressive motility (%) (median (IQR))	25.0 (10.0)	25.0 (5.0)	0.002^b
Immotile sperms (%) (median (IQR))	50.0 (20.0)	50.0 (15.0)	0.100^b
Abnormal morphology (%) (median (IQR))	99.00 (2.00)	99.00 (1.00)	0.580^b

^aNormal distribution, paired -test, ^bnot normal distribution, Wilcoxon test, considered as statistically significant.