Comparison of Triglyceride–Glucose (TyG) Index and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) Index in Prediction of Male Hypogonadism

Table 2

Logistic regression analysis: OR for hypogonadism (n = 88) and compensated hypogonadism (n = 31) according to high/normal HOMA-IR and TyG: subfertile men and healthy controls.

Subfertile group (n = 175)					Control group (n = 192)
	p	Odds ratio (B)	95% CI		p	Odds ratio (B)	95% CI
			Lower	Upper			Lower	Upper
Hypogonadism
HOMA-IR	<0.001	11.0	5.09	23.7	0.020	2.82	1.18	6.74
TyG index	<0.001	4.59	2.30	9.16	0.010	2.84	1.29	6.25
Compensated hypogonadism
HOMA-IR	0.050	0.29	0.08	0.99	0.686	1.60	0.16	15.9
TyG index	0.013	0.15	0.03	0.67	0.871	0.83	0.08	8.13

Hypogonadism: total testosterone < 12 nmol/L; Compensated hypogonadism: total testosterone ≥ 12 nmol/L, and LH > 8.6 IU/L.