Comparison of Triglyceride–Glucose (TyG) Index and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) Index in Prediction of Male Hypogonadism

Table 3

Logistic regression analysis: OR for hypogonadism (n = 85) and compensated hypogonadism (n = 30) according to high/normal HOMA-IR and TyG: overweight and nonoverweight men.

Overweight group (n = 199)					Non-overweight group (n = 153)
	p	Odds ratio	95% CI		p	Odds ratio	95% CI
			Lower	Upper			Lower	Upper
Hypogonadism
HOMA-IR	<0.001	4.42	2.35	8.32	0.003	8.73	2.07	36.9
TyG index	<0.001	3.08	1.68	5.66	0.193	2.14	0.68	6.73
Compensated hypogonadism
HOMA-IR	0.240	0.50	0.16	1.58	Not valid
TyG index	0.050	0.28	0.08	1.00	Not valid

In this analysis, missing values of the body mass index in 15 patients altered the number of men with hypogonadism and those with compensated hypogonadism. Not valid: OR cannot be calculated because the high HOMA-IR/TyG index categories are lacking in subjects with compensated hypogonadism.