Research Article

Male Hyperuricemia Is Associated with Poor Reproductive Outcomes of IVF-ET

Table 1

Baseline characteristic of female and male partners between two groups in the fresh embryo transfer cycles.

CG (N = 65)HG (N = 33)χ2/t/ZP

Female
Age (year)29.28 ± 3.6030.09 ± 3.70−1.0470.298
BMI (kg/m2)22.21 ± 3.6522.38 ± 3.09−0.2300.819
Infertility duration (year)2 (1, 3)2 (1, 3)−0.7460.456
Infertility type (case (%))0.0060.941
 Primary infertility34/65 (52.3)17/33 (51.5)
 Secondary infertility31/65 (47.7)16/33 (48.5)
Basic FSH (mIU/mL)6.86 ± 1.567.44 ± 2.04−1.5540.123
Basic LH (mIU/m)4.38 (2.87, 5.58)4.63 (3.10, 6.55)−0.7520.452
Basic E2 (pg/mL)45.39 ± 14.8445.49 ± 18.93−0.0280.978
AFC (n)11 (8, 15)10 (7, 14)−1.4530.146
Ovulation induction (case (%))2.1880.139
 Short-acting long-term regimen21/65 (32.3)6/33 (18.2)
 Antagonist regimen44/65 (67.7)27/33 (81.8)
Gn used dosage (U)1687.5(1,462.5, 2,025.0)1,575.0 (1,350.0, 1,912.5)−0.8640.388
Gn used duration (day)8 (7, 9)7 (7, 8)−1.3190.187
Average E2 level of follicles with diameter ≥14 mm on hCG trigger day (pg/mL)254.73 (195.58, 389.63)255.31 (193.23, 330.09)−0.2740.784
Endometrial thickness on hCG trigger day (mm)10.45 (9.40, 12.07)11.00 (9.83, 12.40)−1.0270.305
Endometrial classification on hCG trigger day (case (%))#0.1210.728
 A60/65 (92.3)29/33 (87.9)
 B5/65 (7.7)4/33 (12.1)
Number of retrieved oocytes (n)9.26 ± 2.918.42 ± 3.751.2180.226
Number of MII stage oocyte (n)7 (5, 8)6 (4, 8)−0.3330.739
MII stage oocyte rate (%)70.0 (57.9, 100.0)76.2 (54.78, 100.0)−0.6330.527
Number of oocytes used for fertilization (n)9.11 ± 2.978.18 ± 3.781.3280.187
Proportion of fresh embryo transfer cycle (case (%))65 (22.6)33 (26.6)0.7820.377
D3 embryos/blastocyst transfer ratio (case)45/2024/90.1280.720
Number of embryos transferred (n)1.52 ± 0.501.39 ± 0.501.2060.231
Male
Age (year)30.52 ± 4.3330.00 ± 4.230.5690.571
BMI (kg/m2)24.17 ± 3.1324.95 ± 2.32−1.2710.207
Infertility type (case (%))0.4140.520
 Primary infertility39/65 (60.0)22/33 (66.7)
 Secondary infertility26/65 (40.0)11/33 (33.3)
Semen analysis
 Semen volume (mL)3.22 ± 1.342.60 ± 1.152.2790.025
 Sperm concentration (106/mL)84.29 ± 61.5885.50 ± 63.62−0.0910.928
 Total sperm motility (%)52.23 ± 17.0548.09 ± 23.071.0050.317
 Progressive motility (%)41.17 ± 14.5037.96 ± 18.610.9380.351
 Total sperm count (106)249.08 ± 171.59229.10 ± 200.010.5150.608

BMI, body mass index; CG, control group; HG, hyperuricemia group. . #Continuity correction χ2-test.