Research Article

Male Hyperuricemia Is Associated with Poor Reproductive Outcomes of IVF-ET

Table 4

Comparison of baseline characteristics of female and male partners between two groups in IVF cycles.

CG (N = 288)HG (N = 124)χ2/t/ZP

Female
Age (year)29.32 ± 3.5429.60 ± 3.32−0.7530.452
BMI (kg/m2)22.51 ± 3.5422.67 ± 5.55−0.3330.739
Infertility duration (year)2 (1, 3)3 (2, 4)−1.3750.169
Infertility type (case (%))0.2870.592
 Primary infertility152/288 (52.8)69/124 (55.6)
 Secondary infertility8,136/288 (47.2)55/124 (44.4)
Basic FSH (mIU/mL)6.98 (5.90, 8.13)7.04 (6.08, 8.09)−0.3590.719
Basic LH (mIU/mL)4.12 (3.22, 5.46)4.42 (3.13, 5.98)−0.2550.799
Basic E2 (pg/mL)43.00 (34.00, 54.88)43.97 (34.34, 55.00)−1.5990.110
AFC (n)10 (8, 15)10 (8, 14)−0.1020.919
Ovulation induction (case (%))1.3820.240
 Short-acting long-term regimen65/288 (22.9)22/124 (17.70)
 Antagonist regimen222/288 (77.1)102/124 (82.3)
Gn used dosage (U)1,725.00 (1,500.00, 2,025.00)1,725.00 (1,575.00, 1,950.00)−0.7900.429
Gn used duration (day)8 (7, 9)8 (7, 8)−0.3680.713
LH levels on hCG trigger day (mIU/mL)2.26 (1.55, 4.11)2.80 (1.55, 4.66)−1.3880.165
P levels on hCG trigger day (ng/mL)1.19 (0.86, 1.48)0.99 (0.81, 1.48)−1.7770.075
E2 levels on hCG trigger day (pg/mL)2,640.00 (1,878.00, 4,201.00)2,492.00 (1,643.36, 4,275.00)−1.0390.299
Average E2 level of follicles with diameter ≥14 mm on hCG trigger day (pg/mL)408.77 (297.06, 575.08)388.89 (254.67, 570.65)−1.7310.083
Number of retrieved oocytes (n)9 (6, 12)9 (6, 12)−0.4360.663
Number of MII stage oocyte (n)6 (4, 8)6 (4, 8)−0.6920.489
MII stage oocyte rate (%)62.5 (55.6, 75.0)60.0 (53.8, 100.0)−0.1290.897
Number of oocytes used for fertilization (n)9 (6, 12)9 (6, 12)−0.3110.756
Male
Age (year)30.86 ± 4.6329.55 ± 3.532.8140.005
BMI (kg/m2)24.22 ± 3.4925.82 ± 4.09−4.052<0.001
Infertility type (case (%))1.9120.167
Primary infertility172/288 (59.7)83/124 (66.9)
Secondary infertility116/288 (40.3)41/124 (33.1)
Semen analysis
 Semen volume (mL)3.09 ± 1.422.65 ± 1.173.2170.001
 Sperm concentration (106/mL)84.32 ± 56.4672.26 ± 49.212.0650.040
 Total sperm motility (%)51.47 ± 18.3546.56 ± 20.322.4120.016
 Progressive motility (%)40.37 ± 15.5637.53 ± 16.711.6580.098
 Total sperm count (106)236.13 ± 168.79191.71 ± 156.602.5030.013

BMI, body mass index; CG, control group; HG, hyperuricemia group. , , .