Induction of Fetal Hemoglobin <i>In Vivo</i> Mediated by a Synthetic <i>γ</i>-Globin Zinc Finger Activator

<table><i>γ</i>-globin gene expression in phenylhydrazine-treated samples from gg1-VP64 <i>β</i>-YAC bigenic mice. Total RNA isolated from adult spleen was subjected to qPCR analysis using SYBR Green. Primers for human <i>γ</i>-globin were utilized, and the data was normalized to mouse <i>α</i>-globin or Gapdh gene expression. Results are the average of 3 replicates of the gg1-VP64 <i>β</i>-YAC bigenic mouse ± the standard error of the mean (SEM).</table>

Anemia

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Figure 5

Figure 5: Induction of Fetal Hemoglobin <i>In Vivo</i> Mediated by a Synthetic <i>γ</i>-Globin Zinc Finger Activator 

Anemia

Induction of Fetal Hemoglobin In Vivo Mediated by a Synthetic γ-Globin Zinc Finger Activator

Figure 5