Research Article

Evaluation of Serum Leptin Levels and Growth in Patients with β-Thalassaemia Major

Table 1

Serum leptin, ferritin, age, weight, height, BMI -score, BMI, and IGF-1 in -TM patients and controls according to sex.

VariablesSexβ-TM patientsControls value
M/F27/2341/34

Age (years)Male13.6 ± 3.413.7 ± 3.1>0.05
Female12.3 ± 3.312.6 ± 3.0>0.05

Height (cm)Male141.93 ± 15.54156.99 ± 16.07<0.001
Female132.11 ± 12.58147.82 ± 14.45<0.001

Weight (kg)Male34.81 ± 11.7854.05 ± 19.55<0.001
Female30.52 ± 8.9444.62 ± 15.96<0.001

BMI -scoreMale−1.22 ± 1.150.42 ± 1.38<0.001
Female−0.68 ± 1.040.09 ± 1.11<0.004

BMI (kg/m2)Male16.79 ± 2.1221.2 ± 4.65<0.001
Female17.12 ± 2.6219.85 ± 4.67<0.014

S. leptin (ng/mL)Male1.71 ± 1.273.92 ± 1.22<0.001
Female3.27 ± 1.975.95 ± 2.43<0.001

S. ferritin (ng/mL)Male5285.5 ± 3220.2114.14 ± 65.31<0.001
Female5084.0 ± 3260.567.74 ± 30.54<0.001

The significant sex differences (males versus females) for the above parameters within each group of -TM and controls were assessed as follows: , .