Detection of Asymptomatic Sickle Cell Hemoglobin Carriers and Fetal Hemoglobin Regulating Genetic Variants in African Descendants from Oaxaca, Mexico

<div>Validation of (HBB:c.20A &gt; T, p.Glu6Val) substitution. Sequences alignment of products using primers A-E corresponding to Exon 1, IVS-I, and Exon 2. The sequences for the HBB gene (NCBI RefSeq NG_059281.1), one control of a healthy individual, and the twelve HbAS individuals are depicted in the left panel. The vertical line in the electropherograms indicates the [A &gt; T] substitution analyzed and corresponds to (a) Control of a healthy individual (HbAA). (b) Heterozygous Individual (HbAS) and (c) Control of homozygous individual (HbSS). W = A, T.</div>

Anemia

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Figure 2: Detection of Asymptomatic Sickle Cell Hemoglobin Carriers and Fetal Hemoglobin Regulating Genetic Variants in African Descendants from Oaxaca, Mexico 

Figure 2 | Detection of Asymptomatic Sickle Cell Hemoglobin Carriers and Fetal Hemoglobin Regulating Genetic Variants in African Descendants from Oaxaca, Mexico 