Detection of Asymptomatic Sickle Cell Hemoglobin Carriers and Fetal Hemoglobin Regulating Genetic Variants in African Descendants from Oaxaca, Mexico

<div>Identification of new silent variants in the analyzed population. Sequences alignment showing the sequence for HBB gen (NCBI database RefSeq NG_059281.1), one control of a healthy individual, and the twelve HbA-HbS individuals. Representative electropherograms of the CA<b>U</b>/CA<b>C</b> and AC<b>C</b>/AC<b>G</b> variations. (b) and (d) unaffected individuals. (a) and (c) Affected individuals. Variations are marked with a vertical line showing the substituted nucleotide. The RV primer was used for sequencing, so the reverse complementary sequence obtained in the electropherogram was used in the alignment.</div>

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Figure 3: Detection of Asymptomatic Sickle Cell Hemoglobin Carriers and Fetal Hemoglobin Regulating Genetic Variants in African Descendants from Oaxaca, Mexico 

Figure 3 | Detection of Asymptomatic Sickle Cell Hemoglobin Carriers and Fetal Hemoglobin Regulating Genetic Variants in African Descendants from Oaxaca, Mexico 