Detection of Asymptomatic Sickle Cell Hemoglobin Carriers and Fetal Hemoglobin Regulating Genetic Variants in African Descendants from Oaxaca, Mexico

<div>Representative results of the rs766432 SNV by ARMS-PCR. Images show the three possible outcomes when evaluating the rs766432 SNV genotype. Similar results were obtained when assessing the other SNVs. (a) Homozygous individual for alleles with the highest frequency T/T. (b) G/T heterozygous individual and (c) Homozygous individual for alleles with the lower frequency GG. MWM: Molecular weight marker; NC: Negative control; HeLa: positive internal control of HeLa DNA; S: sample, FW 3A and FW 3B: Allele-specific primers forward; RV3: reverse primer with an SNV-free binding site.</div>

Anemia

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Figure 4: Detection of Asymptomatic Sickle Cell Hemoglobin Carriers and Fetal Hemoglobin Regulating Genetic Variants in African Descendants from Oaxaca, Mexico 

Figure 4 | Detection of Asymptomatic Sickle Cell Hemoglobin Carriers and Fetal Hemoglobin Regulating Genetic Variants in African Descendants from Oaxaca, Mexico 