Research Article

TSH Receptor Reduces Hemoglobin S Polymerization and Increases Deformability and Adhesion of Sickle Erythrocytes

Figure 4

TSH was able to increase the deformability of sickled erythrocytes. In this experiment, concentrations of 1, 2, 3, and 5 mIU/L of TSH were used, two controls were also made, one oxygenated and the other deoxygenated (with metabisulphite). The samples were read at absorbances of 540 and 700 nm to calculate the values used in the graph. N = 3. Results expressed as mean ± SEM. , , and vs control, with 95% confidence interval in one-way ANOVA and Tukey post-test.