Acta Neurologica Scandinavica

Research Article

Postprocessing of MRIs Using FreeSurfer in Epilepsy Surgery Patients Provides an Excellent Imaging Marker of Hippocampal Sclerosis but Fails to Separate Subtypes

Table 2

Results of group comparisons using the Wilcoxon Mann–Whitney rank-sum test. For every group comparison, values corrected for multiple comparison ()are listed within each region (WH, CA1, and CA4).


	WH		CA1		CA4
	Effect size	values	Effect size	values	Effect size	values

HS ILAE 1 vs. no-HS	0.98	3.28 × 10 ⁻¹⁰	0.98	2.05 × 10 ⁻¹⁰	0.98	3.07 × 10 ⁻¹⁰
HS ILAE 1 vs. HC	0.98	2.52 × 10 ⁻¹⁷	0.96	5.41 × 10 ⁻¹⁶	0.96	2.28 × 10 ⁻¹⁶
HS ILAE 2 vs. no-HS	1.00	4.88 × 10 ⁻⁴	1.00	4.88 × 10 ⁻⁴	1.0	4.88 × 10 ⁻⁴
HS ILAE 2 vs. HC	1.00	4.80 × 10 ⁻³	0.99	4.80 × 10 ⁻³	1.0	4.80 × 10 ⁻³
HS ILAE 1 vs. HS ILAE 2	0.49	1.00	0.34	1.00	0.57	1.00
No-HS vs. HC	0.41	1.00	0.36	1.00	0.39	1.00
HS vs. no-HS	0.98	1.74 × 10 ⁻¹⁰	0.98	1.11 × 10 ⁻¹⁰	0.98	1.63 × 10 ⁻¹⁰
HS vs. HC	0.98	5.03 × 10 ⁻¹⁸	0.96	1.11 × 10 ⁻¹⁶	0.97	4.19 × 10 ⁻¹⁷

Significant values () are presented in bold. Effect sizes are derived from the Wilcoxon Mann–Whitney (WMW) estimate from the asht package in R, estimating the probability that the VAR of a randomly selected subject from the group listed to the left of the comparison is larger than the VAR of a randomly selected subject from the group to the right. HS = hippocampal sclerosis; ILAE = International League Against Epilepsy; HC = healthy controls; WH = whole hippocampus; CA = cornu ammonis.