Postprocessing of MRIs Using FreeSurfer in Epilepsy Surgery Patients Provides an Excellent Imaging Marker of Hippocampal Sclerosis but Fails to Separate Subtypes

Table 3

Demographic characteristics of patients and controls.

	Healthy controls	HS patients		No-HS
	()	HS ILAE 1 ()	HS ILAE 2 ()	()
Sex
Female	25 (48%)	36 (56%)	4 (80%)	8 (35%)
Male	27 (52%)	28 (44%)	1 (20%)	15 (65%)
Age (years)
Mean (SD)	48 (±21)	36 (±17)	43 (±12)	35 (±13)
Years with epilepsy
Mean (SD)		21 (±16)	36 (±16)	11 (±8.2)
Years with drug resistance
Mean (SD)		17 (±14)	19 (±16)	11 (±8.4)
Laterality
Left	26 (50%)	37 (58%)	1 (20%)	16 (70%)
Right	26 (50%)	27 (42%)	4 (80%)	7 (30%)
Outcome
Non-seizure-free		25 (39%)	1 (20%)	8 (35%)
Seizure-free		39 (61%)	4 (80%)	15 (65%)

Years with epilepsy: years from diagnosis of epilepsy to surgery. Duration drug-resistant: years of drug-resistant epilepsy (i.e., failure of adequate trials of two appropriately chosen and used antiepileptic drug schedules [45]). Laterality: side of operation (patients) or randomized (HC). Outcome: seizure outcome one year after surgery according to the ILAE outcome score [28], where seizure-free patients have a score of 1 (completely seizure-free) and the non-seizure-free patients have any form of seizures with scores 2-5 (from auras only to an increase in baseline seizure days). Categorical values are presented with frequencies and percentages and continuous values with means and standard deviations (SD).