Diagnostic Role of Tau Proteins in Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-Analysis

Table 2

Biomarker estimation assay utilized in the included studies.

S.N.	Study	Specimen	Assay	Sample storage	Test validity
1.	Abu-Rumeileh et al. [11]	CSF	ELISA (Innotest, Belgium)	-80°C	Intra-assay CV: 6%, interassay CV: 20%
2.	Agnello et al. [12]	CSF	CLIA (Lumipulse, Belgium)	-80°C	NR
3.	Bourbouli et al. [17]	CSF	ELISA (Innotest, Belgium)	-80°C	NR
4.	Lanznaster et al. [15]	CSF	NR	NR	NR
5	Paladino et al. [16]	CSF	ELISA (Biosource immunoassay kit, Belgium)	-80°C	Intra-assay CV: <6%, detection limit: <12 pg/mL
6.	Scarafino et al. [13]	CSF	ELISA (Innotest, Belgium)	-80°C	Interassay CV: <10%
7.	Wilke et al. [14]	CSF	ELISA (Innotest, Belgium)	-80°C	NR

CSF: cerebrospinal fluid; ELISA: enzyme-linked immunosorbent assay; CV: coefficient of variation; NR: not reported.