Research Article

Prediction of Basal Ganglia Hematoma Expansion Based on Radiomics and Clinical Characteristics: A Novel Multivariate Predictive Nomogram

Table 1

Baseline characteristics of all patients.

VariablesTotalTraining cohortValidation cohort

m-CTD of hematoma (Hu)65.24 (62.43, 68.24)65.00 (62.37, 68.24)65.63 (62.57, 68.16)0.534
BHV (mL)13.35 (7.28, 20.62)13.94 (7.53, 21.31)12.40 (6.84, 19.42)0.174
BS0.225
 No478 (82.41%)329 (81.03%)149 (85.63%)
 Yes102 (17.59%)77 (18.97%)25 (14.37%)
BHS0.312
 No481 (82.93%)332 (81.77%)149 (85.63%)
 Yes99 (17.07%)74 (18.23%)25 (14.37%)
IS0.525
 No568 (97.93%)396 (97.54%)172 (98.85%)
 Yes12 (2.07%)10 (2.46%)2 (1.15%)
HE1.000
 No413 (71.21%)289 (71.18%)124 (71.26%)
 Yes167 (28.79%)117 (28.82%)50 (28.74%)
Gender0.456
 F179 (30.86%)121 (29.80%)58 (33.33%)
 M401 (69.14%)285 (70.20%)116 (66.67%)
Age (years)56.00 (47.00, 67.00)56.00 (47.00, 67.00)56.00 (46.00, 65.00)0.438
SBP (mmHg)0.828
DBP (mmHg)95.00 (87.00, 104.00)95.00 (86.75, 104.00)95.00 (88.00, 104.00)0.872
Hemoglobin (g/L)138.00 (122.00, 154.00)141.00 (124.00, 153.00)134.50 (119.25, 154.00)0.193
Platelet count (×109/L)207.00 (166.00, 243.00)209.00 (167.00, 243.00)203.00 (157.50, 245.25)0.331
APTT (s)25.30 (22.70, 30.70)25.45 (22.50, 30.80)25.05 (23.10, 30.15)0.831
PT (s)11.70 (10.88, 12.70)11.80 (10.83, 12.80)11.60 (10.90, 12.60)0.909
TT (s)17.10 (16.10, 18.20)17.10 (16.10, 18.20)17.10 (16.10, 18.10)0.912
FIB (g/L)2.96 (2.18, 4.22)2.96 (2.17, 4.36)2.95 (2.18, 4.03)0.962
INR (s)0.98 (0.85, 1.14)0.98 (0.85, 1.13)0.99 (0.86, 1.17)0.416
Blood glucose (mmol/L)8.71 (6.08, 12.07)8.71 (6.18, 12.03)8.71 (5.50, 12.18)0.484
Total cholesterol (mmol/L)4.34 (3.28, 5.49)4.30 (3.23, 5.50)4.40 (3.38, 5.46)0.510
Triglycerides (mmol/L)1.26 (0.77, 1.74)1.24 (0.75, 1.77)1.30 (0.80, 1.71)0.968
Hcy (μmol/L)13.85 (9.65, 18.28)14.09 (9.51, 18.63)13.71 (9.68, 18.16)0.807

Data are expressed as (%), , or median (interquartile range (IQR)). was considered to be statistically significant. IQR = interquartile range; m-CTD = mean CT densities; BHV = baseline hemorrhage volume; BS = blend sign; BHS = basal ganglia hemorrhage; IS = island sign; HE = hematoma expansion; SBP = systolic blood pressure; DBP = diastolic blood pressure; APTT = activated partial thromboplastin time; PT = prothrombin time; TT = thrombin time; FIB = fibrinogen; INR = international normalized ratio; Hcy = homocysteine.